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Towards DNA methylation detection using biosensors

1 Jan 2016

Abstract excerpt

DNA methylation, a stable and heritable covalent modification which mostly occurs in the context of a CpG dinucleotide, has great potential as a biomarker to detect disease, provide prognoses and predict therapeutic responses. It can be detected in a quantitative manner by many different approaches both genome-wide and at specific gene loci, in various biological fluids such as urine, plasma, and serum, which can...

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PMID: 27704092
DOI: 10.1039/c6an01649a

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