Article
Type-2 diabetes mellitus and the frequency of the G22A polymorphism of the adenosine deaminase gene in a mixed population in Brazil.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Jul 2014
Domingos Ana Carolina Bonini, Iacida Edi Carlos, de Oliveira Rafael Monteiro, Bonini-Domingos Claudia Regina, de Mattos Cinara de Cássia Brandão, de Mattos Luiz Carlos
Abstract excerpt
BACKGROUND: Most individuals diagnosed with diabetes mellitus (about 90%) have type 2 disease (T2DM). T2DM is associated with a high genetic predisposition and is characterized by changes in the secretion and action of insulin. There have been reports of increased activity of the adenosine deaminase enzyme in individuals with coronary heart disease and DM. METHODS: We evaluated 162 patients with T2DM and 160...
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