Article
alpha-Linolenic acid, Delta6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction.
The American journal of clinical nutrition - 1 Feb 2007
Baylin Ana, Ruiz-Narvaez Edward, Kraft Peter, Campos Hannia
Abstract excerpt
BACKGROUND: Delta(6)-Desaturase (FADS2) is the rate-limiting step in the polyunsaturated fatty acid (PUFA) biosynthetic pathway. OBJECTIVE: The aim was to test whether the common deletion [T/-] in the promoter of FADS2 affects the PUFA biosynthetic pathway and consequently modifies the effect of alpha-linolenic acid (ALA) on myocardial infarction (MI). DESIGN: Case subjects (n =1694) with a first nonfatal acute...
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