Article
Apolipoprotein-E-deficient mice exhibit an increased susceptibility to disseminated candidiasis.
Medical mycology - 1 Aug 2004
Vonk Alieke G, De Bont Natasja, Netea Mihai G, Demacker Pierre N M, van der Meer Jos W M, Stalenhoef Anton F H, Kullberg Bart Jan
Abstract excerpt
The effect of hyperlipoproteinemia on systemic candidiasis was investigated by assessing the susceptibility of hyperlipoproteinemic, apolipoprotein E (ApoE)-deficient (ApoE -/-) mice to a systemic Candida albicans infection. The absence of ApoE in these mice resulted in an eightfold increase in plasma lipoprotein concentrations in the very low-density lipoprotein (VLDL) fraction, as compared with levels seen in...
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