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Article

sigmaB regulates IS256-mediated Staphylococcus aureus biofilm phenotypic variation.

Journal of bacteriology - 1 Apr 2007

Valle Jaione, Vergara-Irigaray Marta, Merino Nekane, Penadés José R, Lasa Iñigo

Abstract excerpt

Biofilm formation in Staphylococcus aureus is subject to phase variation, and biofilm-negative derivatives emerge sporadically from a biofilm-positive bacterial population. To date, the only known mechanism for generating biofilm phenotypic variation in staphylococci is the reversible insertion/excision of IS256 in biofilm-essential genes. In this study, we present evidence suggesting that the absence of the...

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Identifiers

PMID: 17277051
DOI: 10.1128/JB.01767-06
PMCID: PMC1855799

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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