Article
Molecular characterization of regulatory genes associated with biofilm variation in a Staphylococcus aureus strain.
Journal of microbiology and biotechnology - 1 Jan 2008
Kim Jong-Hyun, Kim Cheorl-Ho, Hacker Jörg, Ziebuhr Wilma, Lee Bok Kwon, Cho Seung-hak
Abstract excerpt
Biofilm formation in association with the intercellular adhesion (icaADBC) gene cluster is a serious problem in nosocomial infections of Staphylococcus aureus. In all 112 S. aureus strains tested, the ica genes were present, and none of these strains formed biofilms. The biofilm formation is known to be changeable by environmental factors. We have found about 30% of phase variation in these strains with treatment...
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