Article
The role of sigmaB in persistence of Staphylococcus epidermidis foreign body infection.
Microbiology (Reading, England) - 1 Sept 2008
Pintens Valerie, Massonet Caroline, Merckx Rita, Vandecasteele Stefaan, Peetermans Willy E, Knobloch Johannes K-M, Van Eldere Johan
Abstract excerpt
Staphylococcal biofilm formation depends on the transcription factor sigma(B). We further investigated the role of sigma(B) in biofilm formation and persistence in vitro and in vivo in a subcutaneous rat model. As expected, expression of all sigma(B) operon genes was transiently higher in the first 6 h of biofilm formation compared to planktonic bacteria, concurrent with a temporary upregulation of icaA and aap...
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