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Article

Influence of IS256 on Genome Variability and Formation of Small-Colony Variants in Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Aug 2017

Kleinert Franziska, Kallies René, Hort Michael, Zweynert Annegret, Szekat Christiane, Nagel Michael, Bierbaum Gabriele

Abstract excerpt

Staphylococcus aureus has acquired resistance to nearly all antibiotics used in clinical practice. Whereas some resistance mechanisms are conferred by uptake of resistance genes, others evolve by mutation. In this study, IS256 has been shown to play a role, e.g., in S. aureus strains displaying intermediate resistance to vancomycin (VISA). To characterize the IS256 insertion sites in the genomes of two closely...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28584147
DOI: 10.1128/AAC.00144-17
PMCID: PMC5527575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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