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Article

Dynamics of Viral RNA Synthesis during Measles Virus Infection

12 May 2005

Abstract excerpt

We propose a reference model of the kinetics of a viral RNA-dependent RNA polymerase (vRdRp) activities and its regulation during infection of eucaryotic cells. After measles virus infects a cell, mRNAs from all genes immediately start to accumulate linearly over the first 5 to 6 h and then exponentially until approximately 24 h. The change from a linear to an exponential accumulation correlates with de novo...

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PMID: 15890929
DOI: 10.1128/jvi.79.11.6900-6908.2005

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