Article
Mannose-binding lectin deficiency does not increase the prevalence of Helicobacter pylori seropositivity.
European journal of gastroenterology & hepatology - 1 Feb 2007
Worthley Daniel L, Mullighan Charles G, Dean Melinda M, Gordon David L, Phillips Peter, Heatley Susan, Young Graeme P, Bardy Peter G
Abstract excerpt
BACKGROUND: Mannose-binding lectin is an immune molecule that can bind to pathogens and initiate the complement cascade. In certain clinical situations, often characterized by immune compromise, mannose-binding lectin deficiency can increase the risk of infectious complications. Helicobacter pylori is one of the most common human infections and can bind mannose-binding lectin. Therefore, we examined whether...
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