Article
Inducible nitric oxide synthase gene promoter polymorphism is associated with increased gastric mRNA expression of inducible nitric oxide synthase and increased risk of gastric carcinoma.
European journal of gastroenterology & hepatology - 1 Feb 2007
Kaise Mitsuru, Miwa Jun, Suzuki Nobuaki, Mishiro Shunji, Ohta Yasuhiko, Yamasaki Takuji, Tajiri Hisao
Abstract excerpt
BACKGROUND AND AIMS: Stimulation of inducible nitric oxide synthase gene expression by Helicobacter pylori, with subsequent overproduction of nitric oxide, has been implicated in gastric carcinogenesis. We investigated whether inducible nitric oxide synthase promoter gene polymorphisms are associated with (a) inducible nitric oxide synthase mRNA expression in the gastric mucosa, and (b) the risk of gastric...
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