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Article

Endothelial nitric oxide synthase gene polymorphism in gastric cancer.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 Dec 2010

Tecder Ünal Müge, Karabulut Halil G, Gümüş-Akay Güvem, Dölen Yusuf, Elhan Atilla, Tükün Ajlan, Ünal Ali Ekrem

Abstract excerpt

BACKGROUND/AIMS: Nitric oxide, a labile compound synthesized by nitric oxide synthase, is a major regulator not only of physiological vascular tonus but also of the abnormal vascularity associated with tumors. Endothelial production of nitric oxide regulates blood flow and angiogenesis and reduces tumor cell adhesion to the endothelium. A high concentration of nitric oxide and its metabolites causes DNA damage...

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PMID: 21331985

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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