Article
Knockdown of V-ATPase subunit A (atp6v1a) impairs acid secretion and ion balance in zebrafish (Danio rerio).
American journal of physiology. Regulatory, integrative and comparative physiology - 1 May 2007
Horng Jiun-Lin, Lin Li-Yih, Huang Chang-Jen, Katoh Fumi, Kaneko Toyoji, Hwang Pung-Pung
Abstract excerpt
In the skin of zebrafish embryo, the vacuolar H(+)-ATPase (V-ATPase, H(+) pump) distributed mainly in the apical membrane of H(+)-pump-rich cells, which pump internal acid out of the embryo and function similarly to acid-secreting intercalated cells in mammalian kidney. In addition to acid excretion, the electrogenic H(+) efflux via the H(+)-ATPases in the gill apical membrane of freshwater fish was proposed to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.