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Article

Combined type-1 plasminogen activator inhibitor and NOD2/CARD15 genotyping predicts complicated Crohn's disease behaviour.

Alimentary pharmacology & therapeutics - 15 Feb 2007

Alvarez-Lobos M, Arostegui J I, Sans M, Tassies D, Piu J, Reverter J C, Pique J M, Yagüe J, Panés J

Abstract excerpt

BACKGROUND: NOD2/CARD15 gene variants have not been universally associated with stricturing behaviour in Crohn's disease. Other behaviour modifying genes could explain these results. AIM: To study the combined influence of NOD2/CARD15 variants and 4G/4G genotype of type-1 plasminogen activator inhibitor (PAI-1) gene on Crohn's disease behaviour. METHODS: One hundred and seventy Crohn's disease patients were...

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Source

Identifiers

PMID: 17269998
DOI: 10.1111/j.1365-2036.2006.03208.x

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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