Article
Predicting complicated Crohn's disease and surgery: phenotypes, genetics, serology and psychological characteristics of a population-based cohort.
Alimentary pharmacology & therapeutics - 1 Aug 2013
Ryan J D, Silverberg M S, Xu W, Graff L A, Targownik L E, Walker J R, Carr R, Clara I, Miller N, Rogala L, Bernstein C N
Abstract excerpt
BACKGROUND: Predictors of complicated Crohn's disease (CD), defined as stricturing or penetrating behaviour, and surgery have largely been derived from referral centre populations. AIM: To investigate whether serological markers, susceptibility genes or psychological characteristics are associated with complicated CD or surgery in a population-based cohort. METHODS: One hundred and eighty-two members of the...
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