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Article

In silico mutation of cysteine residues in the ligand-binding domain of an N-methyl-D-aspartate receptor.

Biochemistry - 27 Feb 2007

Kaye Samantha L, Sansom Mark S P, Biggin Philip C

Abstract excerpt

The precise nature of redox modulation of N-methyl-d-aspartate (NMDA) receptors is still unclear, although it is thought to be related to the formation and breaking of disulfide bonds. Recent structural data demonstrated the way in which disulfide bonds in the ligand-binding core of the NR1 subunit are arranged. However, the structures were not able to reconcile existing experimental data that examined the...

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Identifiers

PMID: 17269660
DOI: 10.1021/bi061462d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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