Article
Human CYP1A1 (cytochrome P(1)450) gene: lack of association between the Msp I restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population.
Pharmacogenetics - 1 Oct 1991
Tefre T, Ryberg D, Haugen A, Nebert D W, Skaug V, Brøgger A, Børresen A L
Abstract excerpt
In this study of 221 lung cancer patients and 212 controls, no association between a Msp I polymorphism in the CYP1A1 gene and an increased risk of lung cancer was found. Histological type, smoking habits and family history were also examined. No associations between the Msp I restriction fragment length polymorphism in the CYP1A1 gene and any of these parameters were found. These results are in contrast to a...
Topics
- Adenocarcinoma
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Blotting, Southern
- Carcinoma
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Cytochrome P-450 Enzyme System
