Article
Mutational epitope analysis and cross-reactivity of two isoforms of Api g 1, the major celery allergen.
Molecular immunology - 1 Apr 2007
Wangorsch Andrea, Ballmer-Weber Barbara K, Rösch Paul, Holzhauser Thomas, Vieths Stefan
Abstract excerpt
For better understanding the cross-reactivity between the major birch pollen and celery allergens, Bet v 1 and Api g 1, respectively, putative epitope areas and structurally important positions for IgE-binding of the isoforms Api g 1.01 and Api g 1.02 were point mutated. The IgE binding capacities were measured in ELISA, the IgE cross-reactivity between the isoforms, mutants and Bet v 1 investigated by...
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