Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for association between multiple complement pathway genes and AMD.

Genetic epidemiology - 1 Apr 2007

Dinu Valentin, Miller Perry L, Zhao Hongyu

Abstract excerpt

In this paper we explore the use of biological knowledge to supplement statistical analysis in identifying genes associated with disease. It has been previously found that the 402H variant in complement factor H (CFH) is associated with risk for developing age related macular degeneration (AMD). By focusing on the single nucleotide polymorphisms (SNPs) in the complement pathway, we were able to use the genotype...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Alleles
Share to Complement Factor H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Macular Degeneration

Share to Models, Genetic

Share to Models, Statistical

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 17266113
DOI: 10.1002/gepi.20204

Genes

CFH
MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for association between multiple complement pathway genes and AMD.PMID 17266113Read ↗

Complement factor H in AMD: Bridging genetic associations and pathobiology.Semantic proximity Read ↗

A 32 kb critical region excluding Y402H in CFH mediates risk for age-related macular degeneration.Semantic proximity Read ↗

Complement factor H variant increases the risk of age-related macular degeneration.Semantic proximity Read ↗

Unraveling a complex genetic disease: age-related macular degeneration.Semantic proximity Read ↗

Complement Factor H Polymorphism, Complement Activators, and Risk of Age-Related Macular DegenerationSemantic proximity Read ↗

Role of genetic factors and inflammation in age-related macular degeneration.Semantic proximity Read ↗

Complement factor H Y402H polymorphism results in diminishing CD4+ T cells and increasing C-reactive protein in plasma.Semantic proximity Read ↗

Protective effect of complement factor B and complement component 2 variants in age-related macular degeneration.Semantic proximity Read ↗

Association between polymorphisms of complement pathway genes and age-related macular degeneration in a Chinese population.Semantic proximity Read ↗

The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited.Semantic proximity Read ↗

Complement factor H polymorphism in age-related macular degeneration.Semantic proximity Read ↗

Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.