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Article

The frequency of cytochrome P450 2E1 polymorphisms in Black South Africans.

Disease markers - 1 Jan 2006

Chelule Paul K, Pegoraro Rosemary J, Gqaleni Nceba, Dutton Michael F

Abstract excerpt

Polymorphisms in the promoter region of the Cytochrome P4502E1 (CYP2E1) gene reportedly modify the metabolic activity of CYP2E1 enzyme, and have been associated with increased susceptibility to squamous cell carcinoma (SCC) of the oesophagus in high prevalence areas such as China. To assess the frequency of these polymorphisms in Black South Africans, a population with a high incidence of oesophageal SCC, this...

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Identifiers

PMID: 17264406
DOI: 10.1155/2006/980392
PMCID: PMC3851364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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