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Article

Genetic polymorphisms of the CYP2E1 gene do not contribute to oral cancer susceptibility in south Indians.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011

Balaji Lakshmi, Singh Krishna Balaji, Bhaskar L V K S

Abstract excerpt

Cytochrome P450 (CYP) is a super family of mixed-function oxidases that are responsible for the human metabolism of drugs and endogenous compounds, as well as environmental and dietary substances. Many CYP enzymes function in the liver, but presence of CYP2E1 in the brain is demonstrating its role in both nicotine and ethanol metabolism. To examine the association between CYP2E1 polymorphism and the risk of oral...

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PMID: 22126492

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