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Article

The mesenchymal substrate influences the epithelial phenotype in a three-dimensional cell culture.

Archives of dermatological research - 1 Sept 2003

Merne Marina, Syrjänen Stina

Abstract excerpt

Cell-matrix interactions are thought to influence epithelial structure, growth, and differentiation. Three-dimensional cell cultures were used to study the effects of the composition of the dermal equivalent on the morphology of epithelium grown from HaCaT skin keratinocytes. Three commercial preparations, a basement membrane preparation from a tumor (matrix 1), two preparations consisting of collagen type I and...

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PMID: 12898149
DOI: 10.1007/s00403-003-0419-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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