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Article

Basal cell carcinoma and pilomatrixoma mirror human follicular embryogenesis as reflected by their differential expression patterns of SOX9 and β-catenin

22 Jan 2010

Abstract excerpt

BACKGROUND: The current classification schemes of adnexal tumours are predominantly based on morphological and immunophenotypical similarities to adult skin structures, whereas a link between the embryology of the skin and the histogenesis of adnexal tumours has been largely neglected. OBJECTIVE: To describe the expression patterns of two proteins with proven relevance for hair follicle homeostasis (SOX9 and...

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PMID: 20105172
DOI: 10.1111/j.1365-2133.2010.09630.x

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