Article
Spread of an emerging Mycobacterium tuberculosis drug-resistant strain in the western Cape of South Africa.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Feb 2007
Victor T C, Streicher E M, Kewley C, Jordaan A M, van der Spuy G D, Bosman M, Louw H, Murray M, Young D, van Helden P D, Warren R M
Abstract excerpt
BACKGROUND: South Africa has a high burden of drug-resistant tuberculosis (TB). METHODS: Routine drug susceptibility testing was performed prospectively over a 2-year period on Mycobacterium tuberculosis isolates in two health districts of the Western Province, South Africa. A cluster of drug-resistant strains that shared a rare mutation in katG315 was found in 64 of the 450 cases identified as having been...
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