Article
An outbreak of drug-resistant tuberculosis caused by a Beijing strain in the western Cape, South Africa.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Dec 2006
Johnson R, Warren R, Strauss O J, Jordaan A M, Falmer A A, Beyers N, Schaaf H S, Murray M, Cloete K, van Helden P D, Victor T C
Abstract excerpt
During October 2005, four children in a school in Cape Town were identified with multidrug-resistant tuberculosis (MDR-TB). Genetic analysis confirmed that these isolates belonged to a single cluster (Beijing cluster 220) and that all harboured a -15 inhA(C-T) promoter mutation demonstrating transmission. Genetic analysis of isolates cultured from patients from the Boland-Overberg-South Cape-Karoo and Cape Town...
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