Article
A linkage study in two families with multiple sclerosis and healthy members with oligoclonal CSF immunopathy.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Dec 2006
Haghighi S, Andersen O, Nilsson S, Rydberg L, Wahlström J
Abstract excerpt
We studied two extended families in which not only multiple sclerosis (MS) segregates, but also approximately 18% of the cerebrospinal fluid (CSF) investigated blood relatives have 'MS immunopathic trait', an oligoclonal CSF immunopathy similar to that seen in MS, but with no neurological symptoms. Both families fit a genetic model for autosomal dominant inheritance for MS immunopathic trait, although with...
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