Article
The current state of multiple sclerosis genetic research.
Annals of the Academy of Medicine, Singapore - 1 May 2000
Rubio J P, Speed T P, Bahlo M, Kilpatrick T J, Foote S J
Abstract excerpt
INTRODUCTION: Multiple sclerosis (MS) is the most common genetic disease of the nervous system with onset usually in young adulthood. Four genome-wide searches in different Caucasian populations for MS susceptibility loci have been performed, but none reported any linkage at a level that would be regarded as significant according to current criteria. Significant linkage of MS to allelic variants of the major...
Topics
- Animals
- Disease Models, Animal
- Encephalomyelitis, Autoimmune, Experimental
- Genetic Linkage
- Genetic Predisposition to Disease
- Genome, Human
- HLA Antigens
- Humans
- Multiple Sclerosis