Article
Forkhead box F1 is essential for migration of mesenchymal cells and directly induces integrin-beta3 expression.
Molecular and cellular biology - 1 Apr 2007
Malin Dmitriy, Kim Il-Man, Boetticher Evan, Kalin Tanya V, Ramakrishna Sneha, Meliton Lucille, Ustiyan Vladimir, Zhu Xiangdong, Kalinichenko Vladimir V
Abstract excerpt
The Forkhead box f1 (Foxf1) transcription factor is expressed in mesenchymal cells of the lung, liver, and gallbladder. Although Foxf1 deficiency causes severe abnormalities in the development of these organs, the molecular mechanisms underlying Foxf1 function remain uncharacterized. In this study we inactivated Foxf1 function in lung mesenchymal cells and mouse embryonic fibroblasts (MEFs) by use of either short...
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