Article
TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis.
Genes & development - 15 Jul 2007
Ogata Souichi, Morokuma Junji, Hayata Tadayoshi, Kolle Gabriel, Niehrs Christof, Ueno Naoto, Cho Ken W Y
Abstract excerpt
The molecular mechanisms governing the cell behaviors underlying morphogenesis remain a major focus of research in both developmental biology and cancer biology. TGF-beta ligands control cell fate specification via Smad-mediated signaling. However, their ability to guide cellular morphogenesis in a variety of biological contexts is poorly understood. We report on the discovery of a novel TGF-beta...
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