Article

GDF11 and its receptor ALK4 independently modulate human myoblast migration and fusion

2025-10-22

Abstract excerpt

<title>Abstract</title> <p> Muscle regeneration is governed by a complex interplay between immune cells and satellite cells (muscle progenitors), orchestrated by signaling molecules of the TGF-β superfamily. Among these, the role of GDF11 activity in skeletal muscle remains contentious, with conflicting evidence suggesting both stimulatory and inhibitory effects. This functional divergence may emerge from the co...

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Literature Corpus work: 86f934ff-1abb-515e-9cd3-b4cd0ee69392
DOI: 10.21203/rs.3.rs-7777108/v1

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