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Article

Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations.

Inflammatory bowel diseases - 1 May 2007

Papadakis Konstantinos A, Yang Huiying, Ippoliti Andrew, Mei Ling, Elson Charles O, Hershberg Robert M, Vasiliauskas Eric A, Fleshner Phillip R, Abreu Maria T, Taylor Kent, Landers Carol J, Rotter Jerome I, Targan Stephan R

Abstract excerpt

BACKGROUND: Antibody reactivity to microbial antigens correlates with distinct Crohn's disease (CD) phenotypes such as fistulizing or fibrostenosing disease. We examined the association between anti-CBir1 and clinical phenotypes and NOD2 variants in a large cohort of adult CD patients. METHODS: Sera and genomic DNA were collected from 731 patients with CD and tested for immune responses to I2, CBir1, oligomannan,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17260364
DOI: 10.1002/ibd.20106

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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