Article
Pancreatic autoantibodies are associated with reactivity to microbial antibodies, penetrating disease behavior, perianal disease, and extraintestinal manifestations, but not with NOD2/CARD15 or TLR4 genotype in a Hungarian IBD cohort.
Inflammatory bowel diseases - 1 Mar 2009
Lakatos Peter Laszlo, Altorjay Istvan, Szamosi Tamas, Palatka Karoly, Vitalis Zsuzsanna, Tumpek Judit, Sipka Sandor, Udvardy Miklos, Dinya Tamas, Lakatos Laszlo, Kovacs Agota, Molnar Tamas, Tulassay Zsolt, Miheller Pal, Barta Zsolt, Stocker Winfried, Papp Janos, Veres Gabor, Papp Maria
Abstract excerpt
BACKGROUND: Pancreatic autoantibodies (PAB) and goblet cell autoantibodies (GAB) are specific for Crohn's disease (CD) and ulcerative colitis (UC), but the sensitivity alone is low. Conventional antibodies and carbohydrates (glycans) are associated with disease phenotype and may be of diagnostic importance in inflammatory bowel disease (IBD). Our aim was to determine the accuracy of PAB and GAB autoantibodies as...
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