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Article

Genetic evidence for ongoing balanced selection at human DNA repair genes ERCC8, FANCC, and RAD51C.

Mutation research - 1 Mar 2007

Wang Eric T, Moyzis Robert K

Abstract excerpt

Using the 2.6 million single nucleotide polymorphism (SNP) genotype datasets from Perlegen Sciences and the Haplotype Map (HapMap) project (Phase I freeze), a probabilistic search for the landscape exhibited by positive Darwinian selection was conducted (Wang et al., 2006). By sorting each high frequency allele by homozygosity, we search for the expected decay of adjacent SNP linkage disequilibrium (LD) at...

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Share to DNA-Binding Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Recombination, Genetic

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Source

Identifiers

PMID: 17257630
DOI: 10.1016/j.mrfmmm.2006.11.030

Genes

ERCC8
FANCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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