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Article

Haplotype and linkage disequilibrium architecture for human cancer-associated genes.

Genome research - 1 Dec 2002

Bonnen Penelope E, Wang Peggy J, Kimmel Marek, Chakraborty Ranajit, Nelson David L

Abstract excerpt

To facilitate association-based linkage studies we have studied the linkage disequilibrium (LD) and haplotype architecture around five genes of interest for cancer risk: ATM, BRCA1, BRCA2, RAD51, and TP53. Single nucleotide polymorphisms (SNPs) were identified and used to construct haplotypes tha...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12466288
DOI: 10.1101/gr.483802
PMCID: PMC187564

Genes

ATM
BRCA1
BRCA2
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12466288-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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