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Article

Genomic regions exhibiting positive selection identified from dense genotype data.

Genome research - 1 Nov 2005

Carlson Christopher S, Thomas Daryl J, Eberle Michael A, Swanson Johanna E, Livingston Robert J, Rieder Mark J, Nickerson Deborah A

Abstract excerpt

The allele frequency spectrum of polymorphisms in DNA sequences can be used to test for signatures of natural selection that depart from the expected frequency spectrum under the neutral theory. We observed a significant (P = 0.001) correlation between the Tajima's D test statistic in full resequencing data and Tajima's D in a dense, genome-wide data set of genotyped polymorphisms for a set of 179 genes. Based on...

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Identifiers

PMID: 16251465
DOI: 10.1101/gr.4326505
PMCID: PMC1310643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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