Article
Global landscape of recent inferred Darwinian selection for Homo sapiens.
Proceedings of the National Academy of Sciences of the United States of America - 3 Jan 2006
Wang Eric T, Kodama Greg, Baldi Pierre, Moyzis Robert K
Abstract excerpt
By using the 1.6 million single-nucleotide polymorphism (SNP) genotype data set from Perlegen Sciences [Hinds, D. A., Stuve, L. L., Nilsen, G. B., Halperin, E., Eskin, E., Ballinger, D. G., Frazer, K. A. & Cox, D. R. (2005) Science 307, 1072-1079], a probabilistic search for the landscape exhibited by positive Darwinian selection was conducted. By sorting each high-frequency allele by homozygosity, we search for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
