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Article

PKCepsilon is essential for gelsolin expression by histone deacetylase inhibitor apicidin in human cervix cancer cells.

Biochemical and biophysical research communications - 16 Mar 2007

Eun Dae-Wook, Ahn Seong Hoon, You Jeong Soo, Park Jong Woo, Lee Eun Kyung, Lee Hyun Nah, Kang Gil Myoung, Lee Jae Cheol, Choi Wahn Soo, Seo Dong-Wan, Han Jeung-Whan

Abstract excerpt

Down-regulation of gelsolin expression is associated with cellular transformation and induction of gelsolin exerts antitumorigenic effects. In this study, we show that protein kinase C (PKC) signaling pathway is required for the induction of gelsolin by the histone deacetylase inhibitor apicidin...

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Identifiers

PMID: 17257588
DOI: 10.1016/j.bbrc.2007.01.046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17257588-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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