Article
Cytoskeletal reorganization induced by retinoic acid treatment of human endometrial adenocarcinoma (RL95-2) cells is correlated with alterations in protein kinase C-alpha.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 1998
Carter C A, Parham G P, Chambers T
Abstract excerpt
We have shown previously that treatment of human endometrial adenocarcinoma (RL95-2) cells with either 13-cis or all-trans retinoic acid results in reorganization of actin filaments, indicating reversion to a stationary phenotype. In the present study, we investigated the role of protein kinase C...
Topics
- Adenocarcinoma
- Antineoplastic Agents
- Carbazoles
- Cell Differentiation
- Cytoskeleton
- Enzyme Inhibitors
- Female
- Humans
- Immunohistochemistry
- Indoles
- Isoenzymes
- Maleimides
- Phenotype
- Protein Kinase C
- Protein Kinase C-alpha
- Staurosporine
- Tretinoin
- Tumor Cells, Cultured