Article
Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: Evidence for a causal relationship.
The American journal of surgical pathology - 1 Feb 2007
Kindelberger David W, Lee Yonghee, Miron Alexander, Hirsch Michelle S, Feltmate Colleen, Medeiros Fabiola, Callahan Michael J, Garner Elizabeth O, Gordon Robert W, Birch Chandler, Berkowitz Ross S, Muto Michael G, Crum Christopher P
Abstract excerpt
Proposed origins of pelvic serous carcinoma include the ovary, fallopian tube, and peritoneum. Prophylactic salpingo-oophorectomies in BRCA+ women have recently identified the fimbria as a site of origin for early serous carcinoma (tubal intraepithelial carcinoma or TIC). We explored the relationship of TIC to pelvic serous carcinomas in consecutive cases with complete adnexal exam (SEE-FIM protocol). Cases...
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