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Article

Reversible anergy of sIgM-mediated signaling in the two subsets of CLL defined by VH-gene mutational status.

Blood - 15 May 2007

Mockridge C Ian, Potter Kathleen N, Wheatley Isla, Neville Louise A, Packham Graham, Stevenson Freda K

Abstract excerpt

The 2 subsets of chronic lymphocytic leukemia (CLL), of worse or better prognosis, likely derive from pre-GC unmutated B cells, or post-GC mutated B cells, respectively. Different clinical behavior could relate to the ability of tumor cells to respond to surface (sIg)-mediated signals. Unmutated...

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Identifiers

PMID: 17255355
DOI: 10.1182/blood-2006-11-056648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17255355-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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