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Article

Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells.

Journal of translational medicine - 25 Jan 2007

Ramakrishna Venky, Vasilakos John P, Tario Joseph D, Berger Marc A, Wallace Paul K, Keler Tibor

Abstract excerpt

Previously, we have successfully targeted the mannose receptor (MR) expressed on monocyte-derived dendritic cells (DCs) using a fully human MR-specific antibody, B11, as a vehicle to deliver whole protein tumor antigens such as the human chorionic gonadotropin hormone (hCGbeta). Since MRs play a role in bridging innate immunity with adaptive immunity we have explored several toll-like receptor (TLR)-specific...

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Source

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Identifiers

PMID: 17254349
DOI: 10.1186/1479-5876-5-5
PMCID: PMC1794405

Genes

TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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