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Article

Expression patterns of inhibitor of apoptosis proteins in malignant pleural mesothelioma

25 Jan 2007

Abstract excerpt

Inhibitor of apoptosis proteins (IAPs) comprise a family of structurally similar proteins, five of which are widely studied in the context of cancer: IAP-1/MIHC/cIAP2, IAP-2/MIHB/cIAP1, livin/ML-IAP/KIAP, survivin, and XIAP/MIHA/hILP. IAPs are overexpressed by most neoplasms, promote tumour cell survival after a wide variety of apoptotic stimuli, and frequently have gene and/or protein expression patterns...

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PMID: 17253596
DOI: 10.1002/path.2121

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