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Identification of Overexpressed Genes in Malignant Pleural Mesothelioma

8 Mar 2021

Abstract excerpt

Malignant pleural mesothelioma (MPM) is a fatal tumor lacking effective therapies. The characterization of overexpressed genes could constitute a strategy for identifying drivers of tumor progression as targets for novel therapies. Thus, we performed an integrated gene-expression analysis on RNAseq data of 85 MPM patients from TCGA dataset and reference samples from the GEO. The gene list was further refined by...

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PMID: 33800494
DOI: 10.3390/ijms22052738

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