Article
Genetic polymorphisms in the promoter of the interferon gamma receptor 1 gene are associated with atopic cataracts.
Investigative ophthalmology & visual science - 1 Feb 2007
Matsuda Akira, Ebihara Nobuyuki, Kumagai Naoki, Fukuda Ken, Ebe Koji, Hirano Koji, Sotozono Chie, Tei Mamoru, Hasegawa Koichi, Shimizu Makiko, Tamari Mayumi, Namba Kenichi, Ohno Shigeaki, Mizuki Nobuhisa, Ikezawa Zenro, Shirakawa Taro, Hamuro Junji, Kinoshita Shigeru
Abstract excerpt
PURPOSE: Previous reports have shown genetic predisposition for atopic dermatitis (AD). Some of the severe complications of AD manifest in the eye, such as cataract, retinal detachment, and keratoconjunctivitis. This study was conducted to examine the genetic association between the atopy-related genes and patients with ocular complications (ocular AD). METHODS: Seventy-eighty patients with ocular AD and 282...
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