Article
Association of polymorphisms in the human IFN-gamma and IL-4 gene with oral lichen planus: a study in an ethnic Chinese cohort.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Jun 2008
Bai Jingping, Lin Mei, Zeng Xin, Zhang Yuanyuan, Wang Zhi, Shen Jun, Jiang Lu, Gao Feng, Chen Qianming
Abstract excerpt
Cytokines have an important role in the pathogenesis and disease progression of oral lichen planus (OLP). The aim of this study was to investigate the impact of gene polymorphisms of T helper cell subtype Th1 and Th2 cytokines, interferon-gamma (IFN-gamma) and interleukin-4 (IL-4), on OLP in an ethnic Chinese cohort. We investigated IFN-gamma gene (IFNG) and IL-4 gene (IL-4) polymorphisms in 151 patients with OLP...
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