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Article

Breast cancer in patients carrying a germ-line CHEK2 mutation: Outcome after breast conserving surgery and adjuvant radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Mar 2007

Meyer Andreas, Dörk Thilo, Sohn Christof, Karstens Johann H, Bremer Michael

Abstract excerpt

BACKGROUND AND PURPOSE: Women carrying mutations in the CHEK2 gene are at an increased breast cancer risk. Data about outcome and prognosis for these patients after standard multimodality treatment are scarce at present. MATERIALS AND METHODS: One-hundred and fifty (150) patients with non-metastasized early-stage breast cancer (T1-2) receiving postoperative radiotherapy following breast-conservative surgery at...

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Source

Identifiers

PMID: 17250914
DOI: 10.1016/j.radonc.2006.12.002

Genes

CHEK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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