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Article

Activation of cAMP-dependent signaling pathway induces mouse organic anion transporting polypeptide 2 expression.

Molecular pharmacology - 1 Apr 2007

Chen Chuan, Cheng Xingguo, Dieter Matthew Z, Tanaka Yuji, Klaassen Curtis D

Abstract excerpt

Rodent Oatp2 is a hepatic uptake transporter for such compounds as cardiac glycosides. In the present study, we found that fasting resulted in a 2-fold induction of Oatp2 expression in liver of mice. Because the cAMP-protein kinase A (PKA) signaling pathway is activated during fasting, the role o...

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PMID: 17244698
DOI: 10.1124/mol.106.030841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17244698-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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