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Article

Functional effects of transgenic expression of cholera toxin in pancreatic beta-cells.

Molecular and cellular endocrinology - 1 Dec 1993

Wogensen L, Ma Y H, Grodsky G M, Robertson R P, Burton F, Sutcliffe J G, Sarvetnick N

Abstract excerpt

Investigation of intracellular pathways of stimulus-secretion signaling in vivo is possible by transgenic expression of agents known to influence specific biochemical interactions in the cells. The objective of the present study was to establish an experimental model for analyzing signal transduction mechanisms in pancreatic beta-cells in vivo, by expressing the cholera toxin A1 subunit under control of the...

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PMID: 7511546
DOI: 10.1016/0303-7207(93)90233-a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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