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Article

Cytosolic expression of SecA2 is a prerequisite for long-term protective immunity.

Cellular microbiology - 1 Jun 2007

Muraille Eric, Narni-Mancinelli Emilie, Gounon Pierre, Bassand Delphine, Glaichenhaus Nicolas, Lenz Laurel L, Lauvau Grégoire

Abstract excerpt

Induction of efficient adaptive T cell-mediated immunity against the intracellular bacterium Listeria monocytogenes requires its successful invasion of host cell cytosol. However, it is not clear whether its cytosolic escape and growth are sufficient to induce T cell-mediated clearance and protection upon secondary infection. To investigate this issue, we have searched for mutants that do not induce long-term...

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Identifiers

PMID: 17244189
DOI: 10.1111/j.1462-5822.2007.00883.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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