Article
VirulentSalmonella entericaSerovar Typhimurium Evades Adaptive Immunity by Preventing Dendritic Cells from Activating T Cells
20 Oct 2006
Abstract excerpt
Dendritic cells (DCs) constitute the link between innate and adaptive immunity by directly recognizing pathogen-associated molecular patterns (PAMPs) in bacteria and by presenting bacterial antigens to T cells. Recognition of PAMPs renders DCs as professional antigen-presenting cells able to prime naïve T cells and initiate adaptive immunity against bacteria. Therefore, interfering with DC function would promote...